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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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1. Introduction

The first clinical study of sildenafil citrate (Viagra®) was published in the 20th edition of the. The first and only study on the safety and effectiveness of sildenafil citrate (Viagra®) has been published in the. The results of the two studies, however, were published in different journals and thus are not directly comparable and could not be compared with those of the current data.

The results of two previous studies are given in. The results of one study showed that sildenafil citrate significantly improved erectile function in men with PAH, but not in men without PAH. The other study showed that sildenafil citrate significantly improved symptoms of heart failure in patients with heart failure with PAH. These studies were published in different journals and thus are not directly comparable.

In the present study, we aimed to determine the safety and effectiveness of sildenafil citrate in patients with PAH and heart failure. This study evaluated sildenafil citrate in men with PAH, heart failure, or other heart failure.

2. Materials and Methods

This was a single-blind, randomized, single-dose, parallel-group, double-masked, double-blind, placebo-controlled study of sildenafil citrate (Viagra®) for treatment of patients with PAH, heart failure, or other heart failure. A total of 90 patients with PAH and heart failure were enrolled into the study. The patients were randomly assigned to sildenafil citrate (20 mg) or placebo (standardized oral dose) for 12 weeks. The study was conducted between December 2012 and February 2013. The patients were randomly assigned to sildenafil citrate (20 mg) or placebo (standardized oral dose) for a 12-week period. The number of patients enrolled into the study was determined by the number of patients with a first heart failure diagnosis and by the number of patients with a first heart failure diagnosis. The patients who did not complete the study, received placebo (sildenafil citrate) or sildenafil citrate (placebo) were excluded. A total of 60 patients with heart failure were included in the study. Patients with PAH, heart failure, or heart failure had a mean age of 70 years old in the sildenafil citrate group and a mean age of 80 years old in the placebo group. The mean time from first heart failure diagnosis to enrollment into the study was 26 weeks. The mean time to enrollment into the study was 18 weeks. The mean number of patients with heart failure was 2.7. The mean time to enrollment into the study was 1.5 years. The patients who completed the study, received placebo (sildenafil citrate) or sildenafil citrate (placebo), and were not in the study group were excluded from the study. The safety of sildenafil citrate in patients with heart failure was evaluated by the safety profile of the patients. Patients with heart failure, liver or kidney impairment, and a severe history of PAH or heart failure were excluded. This study was approved by the Institutional Review Board of the National Hospital Organization of Pakistan (NHP). The study was performed in accordance with the guidelines and regulations of the Institutional Review Board of the National Hospital Organization of Pakistan (NHP). Written informed consent was obtained from all patients before enrolment. This study was registered at the Clinical Trials Registry, Institutional Register No.: NCT0090788.

Study patients were randomly assigned to sildenafil citrate (20 mg) or placebo (standardized oral dose) for a 12-week period. Patients with heart failure, liver or kidney impairment, or a severe history of PAH or heart failure were excluded from the study. The safety of sildenafil citrate was evaluated by the following parameters: the number of patients with heart failure, heart failure, or liver impairment who received placebo; the number of patients who received sildenafil citrate and placebo; the number of patients who received sildenafil citrate and placebo; the number of patients who received sildenafil citrate and placebo; and the number of patients who received sildenafil citrate and placebo. Patients were excluded if they were hospitalized, had a significant increase in their blood pressure, had a history of PAH, were taking other drugs that were used for PAH, or were unable to use sildenafil citrate (for example, nitrates, amiodarone, or riociguat).

3. Results

The mean age of patients was 67.

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Viagra Connect is available without a Prescription but requires a brief consultation with the Pharmacist. It is available in a 4 pack or an 8 pack. Viagra Connect contains Sildenafil 50mg which works by relaxing the penis blood vessels, allowing blood to flow when you get aroused causing erections and potency. Viagra Connect will only help men become erect if you are aroused. Only for adult use, men 18 years plus.

How to be taken:

  • The recommended dose is one 50 mg tablet taken with water approximately one hour before bedtime activity
  • The maximum recommended dosing frequency is once per day
  • The onset of sexual activity may be delayed if Viagra Connect is taken with food, compared to without food
  • Please read Instructions provided with the product carefully before taking.

VIAGRA CONNECT is not to be taken if:

  • There is no problem with gaining erections.
  • Nitrate medicine is taken for chest pain or heart failure
  • Amyl nitrite, so-called “poppers”, is taken as recreational drugs
  • Riociguat (or other guanylate cyclase stimulators) is taken for high blood pressure in the lungs
  • Ritonavir is taken for the treatment of HIV
  • Your Doctor has advised you to avoid activity because of a problem with your heart or blood vessels
  • You have a heart problem such as a recent heart attack or stroke (within the last 6 months), Chest pain (Angina) or severe Heart failure (reduced pumping capacity of the heart)
  • You have a liver problem
  • You have low blood pressure (below 90/50 mmHg) which can cause symptoms such as tiredness, dizziness, light-headedness, feeling sick, clammy skin, depression, loss of consciousness, or blurry vision
  • Loss of vision has occurred before because of nerve damage in the eyes, such as non-arteritic anterior ischaemic optic neuropathy (NAION); or have a rare inherited eye disease, such as retinitis pigmentosa
  • You have a deformed penis
  • You are a woman
  • You are under 18 years of age
  • You are allergic to sildenafil or any of the other ingredients of this medicine

Please read instructions carefully provided.

Viagra Connect is a fast acting drug for erectile dysfunction which can last up to 4 hours and takes effect within 30 minutes after administration.

Sildenafil Citrate 50 mg Tablets: This tablet is specifically formulated to treat the symptoms of erectile disfunction and is highly effective in treating it, the most common sexual disorder affecting men over the age of 40 years. Provides a solution to erectile dysfunction in men who suffer from impotence due to conditions such as heart disease or diabetes, or who have problems with their physical or mental health.

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About Viagra Connect

Viagra Connect is a fast-acting drug for erectile dysfunction which can last up to 4 hours and takes effect within 30 minutes after administration.

It works by relaxing the blood vessels in the penis, allowing blood to flow into the penis when you get sexually excited and causing the desired stiffness.

It takes up to 4 hours for Viagra Connect to work, it is taken on an empty stomach and is usually half an hour before sex.

It does not affect sex performance. It will allow you toumpery treat erectile dysfunction by improving sexual function.

Please read the manufacturer's printed information information carefully before you use Viagra Connect.How to take
  • Viagra Connect is to treat erectile dysfunction
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What is Dapoxetine?

Dapoxetine is used to treat premature ejaculation in men aged 18 to 64. Premature ejaculation is when a man ejaculates (orgasms) more quickly with less sexual stimulation than the man or his partner would like.

Dapoxetine works by increasing the amount of serotonin in the brain, which helps to delay ejaculation and increase the time to ejaculation.

Dapoxetine is only for use by men aged 18 to 64.

How does Dapoxetine work?

Dapoxetine belongs to a drug class called SSRIs. It is a type of medication called a SSRI. Dapoxetine works by blocking the reuptake of serotonin, which occurs in both men and women. This allows increased serotonin levels to be reabsorbed and released, resulting in increased levels being taken away from the brain.

Dapoxetine may be used to treat any of the following conditions:

Premature ejaculation

Erectile dysfunction

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Disease interactions with other drugs

Dosage: See the

The recommended dose is one tablet within 24 hours. Dapoxetine may be taken with or without food.

Dapoxetine belongs to a class of drugs called phosphodiesterase type 5 inhibitors. This medication works by helping to improve the amount of blood flow to the penis, which may help to increase ability to have an erection.

Dapoxetine is only intended to treat premature ejaculation in men aged 18 to 64 years.

What are the side effects of Dapoxetine?

If you experience any of the following serious side effects, stop taking Dapoxetine and contact your doctor immediately:

  • Allergic reactions to ingredients
  • Prolonged or painful erection (priapism)
  • Heart problems
  • Low blood pressure
  • Elevated levels of urine or blood cells
  • An increase in the number of white blood cells (e.g.